Research Use Only

Computational Consultingfor Nanoparticle Research

Expert-led modeling and analysis for neurotoxicology, drug delivery, and environmental health research. We help you design better experiments and strengthen grant proposals.

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Monte Carlo Simulation
10,000+
Parameter iterations
🧬
Safety Window
Ebind < E < Emax
Turnaround
48-72h
Publication-ready reports

The Challenge

Nanoplastics have been detected in human brain tissue, blood, and placenta. Researchers need to understand particle-cell interactions, but wet-lab experiments are slow, expensive, and can only test limited conditions.

$100K+
Typical wet-lab study cost
6-12 mo
Time per experimental iteration
10-20
Conditions testable per study

Powered by Advanced AI

Combining decades of physics expertise with modern machine learning to deliver faster, more comprehensive analyses.

🧠

LLM-Enhanced Research

Rapid literature synthesis across thousands of publications for comprehensive hypothesis generation.

⚙

Monte Carlo + ML

Hybrid simulations combining proven physics models with machine learning optimization.

📊

Intelligent Analysis

AI-assisted parameter sensitivity analysis and automated report generation.

Services

Expert consulting delivered as clear, actionable reports to support your research.

Mechanistic Appendix

$2,500

For grant proposals and publications

  • Literature-based estimates
  • Publication-ready figures
  • Hypothesis generation
  • Methods section draft
  • 48-72 hour delivery
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Popular

Pilot Partner Sprint

$25-50K

8-week collaboration

  • Weekly working sessions
  • 2-4 scenario analyses
  • Custom report templates
  • Experiment design support
  • Go/no-go criteria
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Enterprise R&D

Custom

For pharma preclinical teams

  • De-risking study design
  • Multi-scenario modeling
  • Safety threshold analysis
  • Dedicated support
  • Regulatory-aware outputs
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How We Work

1

Consultation

Understand your research goals and experimental context

2

Analysis

Literature review, parameter estimation, scenario modeling

3

Synthesis

Generate figures, hypotheses, and recommendations

4

Delivery

Report with clear limitations and suggested next steps

Use Cases

📝

Grant Proposal Support

Publication-quality figures, preliminary computational data, and methods sections that strengthen funding applications.

🎯

Experiment Prioritization

Identify which parameters matter most before committing to expensive wet-lab studies. Focus resources on high-impact experiments.

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Organ-on-Chip / Organoid Design

Model nanoparticle behavior in BBB chips, neural organoids, and barrier tissue systems before fabrication.

🛡

Preclinical Safety Assessment

Binding energy and safety threshold analysis to de-risk nanoparticle drug delivery candidates.

Mihaela Cosma

Mihaela Cosma

Founder & Principal Scientist

Medical physicist with 40+ years of computational modeling experience. Pioneered Monte Carlo microdosimetry for cancer therapy at Memorial Sloan-Kettering. Published in IJROBP, NATO ASI Series, and Journal of Nuclear Medicine.

Applying decades of cellular-level energy modeling expertise to the emerging challenge of nanoplastics in biological systems.

Licensed Medical Physicist (NY) Columbia University Memorial Sloan-Kettering Monte Carlo Simulation AAPM Lifetime Member

Ready to accelerate your research?

Whether you're writing a grant, designing experiments, or de-risking a preclinical program, we can help.

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